MW108 hydrochloride is a selective inhibitor of p38α MAPK, with an affinity (Ki) of 114 nM. This compound demonstrates the ability to mitigate beta-amyloid-induced synaptic impairments and cognitive dysfunction, making it a valuable tool for studying neurodegenerative disorders. Its central nervous system penetration enhances its utility in research focused on Alzheimer's disease and related pathologies.
MW108 hydrochloride is a selective inhibitor of p38α MAPK, with an affinity (Ki) of 114 nM. This compound demonstrates the ability to mitigate beta-amyloid-induced synaptic impairments and cognitive dysfunction, making it a valuable tool for studying neurodegenerative disorders. Its central nervous system penetration enhances its utility in research focused on Alzheimer's disease and related pathologies.
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