N-(Amino-PEG2)-N-bis(PEG3-azide) is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimeras) synthesis, featuring an azide functionality essential for click chemistry applications. It can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds, facilitating the development of bifunctional molecules. Additionally, this linker supports strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN modified substrates, making it a versatile tool for innovative research in targeted protein degradation.
N-(Amino-PEG2)-N-bis(PEG3-azide) is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimeras) synthesis, featuring an azide functionality essential for click chemistry applications. It can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing compounds, facilitating the development of bifunctional molecules. Additionally, this linker supports strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN modified substrates, making it a versatile tool for innovative research in targeted protein degradation.
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