N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based linker designed for the synthesis of PROTAC (Proteolysis Targeting Chimeras) compounds. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. It serves as a vital tool for researchers in the field of targeted protein degradation, facilitating the development of novel therapeutic strategies.
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based linker designed for the synthesis of PROTAC (Proteolysis Targeting Chimeras) compounds. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. It serves as a vital tool for researchers in the field of targeted protein degradation, facilitating the development of novel therapeutic strategies.
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