N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker designed for the effective synthesis of protein-targeting chimeras. This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkynes or DBCO/BCN groups, respectively. Its versatility allows for precise modifications in drug development and the exploration of targeted protein degradation mechanisms in biochemical research.
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker designed for the effective synthesis of protein-targeting chimeras. This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkynes or DBCO/BCN groups, respectively. Its versatility allows for precise modifications in drug development and the exploration of targeted protein degradation mechanisms in biochemical research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
