N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker designed for synthesizing bifunctional molecules. This compound features an azide moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it is capable of undergoing strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN functionalized molecules, making it a versatile tool for chemical biology applications, including targeted protein degradation studies.
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker designed for synthesizing bifunctional molecules. This compound features an azide moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it is capable of undergoing strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN functionalized molecules, making it a versatile tool for chemical biology applications, including targeted protein degradation studies.
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