N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This compound functions as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds. These properties make it a valuable tool in chemical biology and drug discovery research.
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This compound functions as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds. These properties make it a valuable tool in chemical biology and drug discovery research.
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