N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with reactants containing DBCO or BCN moieties. Its biocompatibility and versatility make it ideal for constructing targeted protein degradation systems in chemical biology research.
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with reactants containing DBCO or BCN moieties. Its biocompatibility and versatility make it ideal for constructing targeted protein degradation systems in chemical biology research.
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