N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. It features an azide functional group that facilitates click chemistry via copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it a versatile tool for conjugating various biomolecules in chemical biology research.
N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. It features an azide functional group that facilitates click chemistry via copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it a versatile tool for conjugating various biomolecules in chemical biology research.
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