N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a poly(ethylene glycol)-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds, making it a versatile tool for researchers in chemical biology and drug development.
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a poly(ethylene glycol)-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds, making it a versatile tool for researchers in chemical biology and drug development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
