N-Azido-PEG4-N-Boc-N-PEG3-Boc

Catalog No.: A82565
PROTAC Linker
N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based linker designed for PROTAC synthesis, facilitating targeted protein degradation. Featuring an azide functional group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, specifically with DBCO or BCN-containing molecules. This reagent is essential for researchers developing novel therapeutic modalities through targeted degradation pathways.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$45.00
In stock
100mg
$200.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based linker designed for PROTAC synthesis, facilitating targeted protein degradation. Featuring an azide functional group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, specifically with DBCO or BCN-containing molecules. This reagent is essential for researchers developing novel therapeutic modalities through targeted degradation pathways.
Product Information
Catalog NumA82565
FormulaC28H54N4O11
Molecular Weight622.75
CAS Number2093152-85-1
SMILESO=C(OC(C)(C)C)N(CCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(OC(C)(C)C)=O
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