Fig. 1 · Structure
Documents & Downloads
N-Boc-15-aminopentadecanoic acid
PROTAC Linker
N-Boc-15-aminopentadecanoic acid is a PROTAC linker characterized by its alkane chain, featuring a terminal carboxylic acid and Boc-protected amino groups. This compound facilitates the synthesis of PROTACs by enabling the formation of stable amide bonds with primary amine groups through reaction with activators like EDC or HATU. The Boc protective group can be deprotected under mild acidic conditions to yield the free amine, thus enhancing the versatility in the development of targeted protein degradation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1661040-68-1 |
| Applications | PROTAC Linker |
| Formula | C20H39NO4 |
| Molecular Weight | 357.53 |
| SMILES | O=C(O)CCCCCCCCCCCCCCNC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.