N-Boc-15-aminopentadecanoic acid is a PROTAC linker characterized by its alkane chain, featuring a terminal carboxylic acid and Boc-protected amino groups. This compound facilitates the synthesis of PROTACs by enabling the formation of stable amide bonds with primary amine groups through reaction with activators like EDC or HATU. The Boc protective group can be deprotected under mild acidic conditions to yield the free amine, thus enhancing the versatility in the development of targeted protein degradation strategies.
N-Boc-15-aminopentadecanoic acid is a PROTAC linker characterized by its alkane chain, featuring a terminal carboxylic acid and Boc-protected amino groups. This compound facilitates the synthesis of PROTACs by enabling the formation of stable amide bonds with primary amine groups through reaction with activators like EDC or HATU. The Boc protective group can be deprotected under mild acidic conditions to yield the free amine, thus enhancing the versatility in the development of targeted protein degradation strategies.
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