N-Boc-7-aminoheptanoic acid functions as a PROTAC linker, facilitating the synthesis of targeted protein degradation agents. This compound features an alkane chain with a terminal carboxylic acid and a Boc-protected amino group, allowing for efficient conjugation reactions. The terminal carboxylic acid can form stable amide bonds with primary amines when activated by agents such as EDC or HATU. The Boc group is removable under mild acidic conditions, resulting in the release of the free amine for further applications.
N-Boc-7-aminoheptanoic acid functions as a PROTAC linker, facilitating the synthesis of targeted protein degradation agents. This compound features an alkane chain with a terminal carboxylic acid and a Boc-protected amino group, allowing for efficient conjugation reactions. The terminal carboxylic acid can form stable amide bonds with primary amines when activated by agents such as EDC or HATU. The Boc group is removable under mild acidic conditions, resulting in the release of the free amine for further applications.
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