N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring a propargyl group, this compound facilitates click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing molecules. Its versatility supports research applications in targeted protein degradation and novel therapeutic development.
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring a propargyl group, this compound facilitates click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing molecules. Its versatility supports research applications in targeted protein degradation and novel therapeutic development.
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