N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5

Catalog No.: A82525
PROTAC Linker
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker designed for synthesizing proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of PROTACs by linking target proteins to E3 ligases, thereby promoting targeted degradation. Its unique structure allows for effective conjugation with various biomolecules, enabling advanced research into protein regulation and targeted therapeutics.
Grouped product items
Size Price Stock Qty
1mg
$145.00
In stock
5mg
$325.00
In stock
10mg
$500.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker designed for synthesizing proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of PROTACs by linking target proteins to E3 ligases, thereby promoting targeted degradation. Its unique structure allows for effective conjugation with various biomolecules, enabling advanced research into protein regulation and targeted therapeutics.
Product Information
Catalog NumA82525
FormulaC45H60ClN3O10
Molecular Weight838.43
CAS Number2107273-28-7
SMILESCC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCC(ON3C(CCC3=O)=O)=O)C(C=CC=C4)=C4C/2(C)C)=[N+](CCOCCOCCOCCOC)C5=CC=CC=C51.[Cl-]
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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