N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 is a PEG-conjugated linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates targeted protein degradation by linking an E3 ligase to a protein of interest, thereby promoting ubiquitination and subsequent proteolytic degradation. Its application is crucial in the development of novel therapeutic strategies for diseases caused by dysregulated proteins.
N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 is a PEG-conjugated linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates targeted protein degradation by linking an E3 ligase to a protein of interest, thereby promoting ubiquitination and subsequent proteolytic degradation. Its application is crucial in the development of novel therapeutic strategies for diseases caused by dysregulated proteins.
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