N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker designed to facilitate the synthesis of PROTACs. This compound features an alkyne functional group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications in chemical biology include the development of targeted protein degradation strategies, allowing for innovative therapeutic approaches in drug discovery and research.
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker designed to facilitate the synthesis of PROTACs. This compound features an alkyne functional group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications in chemical biology include the development of targeted protein degradation strategies, allowing for innovative therapeutic approaches in drug discovery and research.
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