N-Nitrosodiethylamine (Diethylnitrosamine, DEN) is a highly potent hepatocarcinogenic dialkylnitrosamine found in tobacco smoke, water, cheddar cheese, cured and fried foods, and various alcoholic beverages. It induces alterations in nuclear enzymes involved in DNA repair and replication, contributing to its carcinogenicity. DEN causes tumors across multiple animal species, primarily affecting the nasal cavity, trachea, lung, esophagus, and liver.
N-Nitrosodiethylamine (Diethylnitrosamine, DEN) is a highly potent hepatocarcinogenic dialkylnitrosamine found in tobacco smoke, water, cheddar cheese, cured and fried foods, and various alcoholic beverages. It induces alterations in nuclear enzymes involved in DNA repair and replication, contributing to its carcinogenicity. DEN causes tumors across multiple animal species, primarily affecting the nasal cavity, trachea, lung, esophagus, and liver.
Product Information
Catalog Num
A24145
Formula
C4H10N2O
Molecular Weight
102.14
CAS Number
55-18-5
SMILES
CCN(CC)N=O
Synonyms
Diethylnitrosamine; DEN
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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