N-PEG3-N'-(propargyl-PEG4)-Cy5 is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an alkyne group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications extend to chemical biology and drug discovery, particularly in the development of innovative therapeutic strategies targeting specific protein interactions.
N-PEG3-N'-(propargyl-PEG4)-Cy5 is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an alkyne group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications extend to chemical biology and drug discovery, particularly in the development of innovative therapeutic strategies targeting specific protein interactions.
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