NAMPT activator-9 is an allosteric, non-competitive activator of nicotinamide adenine dinucleotide (NAD+) biosynthesis, targeting the enzyme NAMPT with an EC50 of 3.366 μM. This compound enhances NAMPT's enzymatic activity, leading to increased intracellular NAD+ levels. Furthermore, NAMPT activator-9 has been shown to restore myotube diameter and decrease the expression of muscle atrophy markers Atrogin-1 and MuRF1, making it a valuable tool for research on muscle atrophy and related metabolic disorders.
NAMPT activator-9 is an allosteric, non-competitive activator of nicotinamide adenine dinucleotide (NAD+) biosynthesis, targeting the enzyme NAMPT with an EC50 of 3.366 μM. This compound enhances NAMPT's enzymatic activity, leading to increased intracellular NAD+ levels. Furthermore, NAMPT activator-9 has been shown to restore myotube diameter and decrease the expression of muscle atrophy markers Atrogin-1 and MuRF1, making it a valuable tool for research on muscle atrophy and related metabolic disorders.
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