Nazartinib mesylate

Catalog No.: A21741
EGFR inhibitor
Nazartinib mesylate (EGF816 mesylate) is a novel, covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min?1 on EGFR(L858R/790M) mutant, respectively.
Grouped product items
Product Name Price Stock Qty
Nazartinib mesylate 1mg
$320.00
In stock
Nazartinib mesylate 5mg
$960.00
In stock
Nazartinib mesylate 10mg
$1,600.00
In stock
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Biological Activity
Discription Nazartinib mesylate (EGF816 mesylate) is a novel, covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min?1 on EGFR(L858R/790M) mutant, respectively.
Targets
Target Value
Product Information
Catalog Num A21741
Formula C27H35ClN6O5S
Molecular Weight 591.12
CAS Number 1508250-72-3
SMILES O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@H]4CN(C(/C=C/CN(C)C)=O)CCCC4.CS(=O)(O)=O
Synonyms EGF816 (mesylate), EGF 816, EGF-816
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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