EGF816 (Nazartinib)

Catalog No.: A14416

EGFR T790M inhibitor

EGF816 (Nazartinib)

EGF816 (Nazartinib) Chemical Structure

CAS NO. 1508250-71-2

EGF816 is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

EGF816 is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.2 mL 101.01 mL 202.01 mL
0.5 mM 4.04 mL 20.2 mL 40.4 mL
1 mM 2.02 mL 10.1 mL 20.2 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 495.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14416
Actions Inhibitor
M. Wt 495.02
Formula C26H31ClN6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1508250-71-2
Synonyms EGF-816, EGF 816, Nazartinib
SMILES CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl

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