NB-598 Maleate

Catalog No.: A15180

SE inhibitor

NB-598 Maleate

NB-598 Maleate Chemical Structure

CAS NO. 155294-62-5, 136719-26-1

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.

Availability: In stock

Package Price Qty
5 mg
$200.00
10 mg
$300.00
50 mg
$780.00
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  • Weber RA, .et al. Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation, Mol Cell, 2020, Feb 6;77(3):645-655 PMID: 31983508
  • Garcia-Bermudez J, .et al. Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death, Nature, 2019, Feb 13 PMID: 30760928

Biological Activity

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.68 mL 88.38 mL 176.76 mL
0.5 mM 3.54 mL 17.68 mL 35.35 mL
1 mM 1.77 mL 8.84 mL 17.68 mL
5 mM 0.35 mL 1.77 mL 3.54 mL

*The above data is based on the productmolecular weight 565.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15180
Actions Inhibitor
M. Wt 565.74
Formula C31H35NO5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 155294-62-5, 136719-26-1
Synonyms NB598 Maleate, NB 598 Maleate
SMILES CCN(C/C=C/C#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3.C(=C\C(=O)O)\C(=O)O

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