Nedisertib

Catalog No.: A17055

DNA-PK inhibitor

Nedisertib

Nedisertib Chemical Structure

CAS NO. 1637542-33-6

Nedisertib, also known as M-3814, MSC2490484A, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities.

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5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $720.00

Special Price $576.00

100 mg

Regular Price: $1,220.00

Special Price $976.00

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Biological Activity

Nedisertib, also known as M-3814, MSC2490484A, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities.
In vitro DMSO 86 mg/mL (178.45 mM)
Water Insoluble
Ethanol 2 mg/mL (4.15 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.75 mL 103.75 mL 207.51 mL
0.5 mM 4.15 mL 20.75 mL 41.5 mL
1 mM 2.08 mL 10.38 mL 20.75 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17055
Actions Inhibitor
CAS No. 1637542-33-6
Formula C24H21ClFN5O3
M. Wt 481.91
Purity >98%
Synonyms MSC2490484A, MSC-2490484A; MSC 2490484A, M3814, M-3814, M 3814
SMILES COC1=CC=C([[email protected]@H](O)C2=CC(C3=C(C=CC(N4CCOCC4)=C5)C5=NC=N3)=C(F)C=C2Cl)N=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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