Nelarabine (Arranon)

Catalog No.: A10632

Nelarabine (Arranon)

Nelarabine (Arranon) Chemical Structure

CAS NO. 121032-29-9

Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $400.00

Special Price $320.00

100 mg

Regular Price: $700.00

Special Price $560.00

10mM * 1mL in DMSO
$80.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity.
Targets
DNA synthesis (PER-255 cells) DNA synthesis (HSB2 cells) DNA synthesis (ALL-SIL cells) DNA synthesis (JURKAT cells)
67 nM0.44 μM1.24 μM2.15 μM
In vitro (25°C) DMSO 60 mg/mL (201.83 mM)
Water 3 mg/mL (10.09 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.64 mL 168.18 mL 336.36 mL
0.5 mM 6.73 mL 33.64 mL 67.27 mL
1 mM 3.36 mL 16.82 mL 33.64 mL
5 mM 0.67 mL 3.36 mL 6.73 mL

*The above data is based on the productmolecular weight 297.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10632
Actions N/A
M. Wt 297.3
Formula C11H15N5O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 121032-29-9
Synonyms 506U78
SMILES COC1=NC(=NC2=C1N=CN2[[email protected]]3[[email protected]]([[email protected]@H]([[email protected]](O3)CO)O)O)N

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