NEP28 is a selective androgen receptor modulator with a reported EC50 of 2.90 nM in 22RV1 cells. It enhances the activity of the Aβ-degrading enzyme neprilysin, demonstrating potential therapeutic benefits in muscle and brain tissue while mitigating adverse effects in the prostate as observed in rat models. This compound is suitable for research applications targeting osteoporosis, sarcopenia, and Alzheimer's disease.
NEP28 is a selective androgen receptor modulator with a reported EC50 of 2.90 nM in 22RV1 cells. It enhances the activity of the Aβ-degrading enzyme neprilysin, demonstrating potential therapeutic benefits in muscle and brain tissue while mitigating adverse effects in the prostate as observed in rat models. This compound is suitable for research applications targeting osteoporosis, sarcopenia, and Alzheimer's disease.
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