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Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.83 mL | 109.15 mL | 218.3 mL |
| 0.5 mM | 4.37 mL | 21.83 mL | 43.66 mL |
| 1 mM | 2.18 mL | 10.92 mL | 21.83 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.37 mL |
*The above data is based on the productmolecular weight 458.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21767 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 133825-81-7 |
| Formula | C27H40ClN3O |
| M. Wt | 458.08 |
| Purity | >98% |
| Synonyms | PD-132301 hydrochloride, PD132301, PD 132301; ATR101 hydrochloride, ATR 101, ATR-101 |
| SMILES | O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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