NF-56-EJ40 is a highly selective antagonist of the human SUCNR1 (GPR91), demonstrating potent inhibitory activity with an IC50 of 25 nM and a Ki of 33 nM. Its specificity minimizes interaction with rat SUCNR1, showcasing a Ki value of 17.4 nM when assessed against a humanized rat model. This compound is valuable for research applications targeting metabolic disorders and the role of SUCNR1 in physiological processes.
NF-56-EJ40 is a highly selective antagonist of the human SUCNR1 (GPR91), demonstrating potent inhibitory activity with an IC50 of 25 nM and a Ki of 33 nM. Its specificity minimizes interaction with rat SUCNR1, showcasing a Ki value of 17.4 nM when assessed against a humanized rat model. This compound is valuable for research applications targeting metabolic disorders and the role of SUCNR1 in physiological processes.
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