NG25

Catalog No.: A15185

TAK1/MAP4K2 inhibitor

NG25

NG25 Chemical Structure

CAS NO. 1315355-93-1

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

Availability: In stock

Package Price Qty
5 mg
$225.00
10 mg
$425.00
25 mg
$825.00
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Biological Activity

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.
In vitro DMSO 85 mg/mL (158.11 mM)
Water Insoluble
Ethanol 2 mg/mL (3.72 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.6 mL 93.01 mL 186.02 mL
0.5 mM 3.72 mL 18.6 mL 37.2 mL
1 mM 1.86 mL 9.3 mL 18.6 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 537.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15185
Actions Inhibitor
CAS No. 1315355-93-1
Formula C29H30F3N5O2
M. Wt 537.58
Purity >98%
Synonyms NG 25, NG-25
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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