NG25

Catalog No.: A15185

TAK1/MAP4K2 inhibitor

NG25 Chemical Structure

CAS NO. 1315355-93-1

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

Availability: In stock

Package Price Qty
5 mg
$225.00
10 mg
$425.00
25 mg
$825.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.6 mL 93.01 mL 186.02 mL
0.5 mM 3.72 mL 18.6 mL 37.2 mL
1 mM 1.86 mL 9.3 mL 18.6 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 537.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15185
Actions Inhibitor
M. Wt 537.58
Formula C29H30F3N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1315355-93-1
Synonyms NG 25, NG-25
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F

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