NGI-1

Catalog No.: A18706

OST inhibitor

NGI-1

NGI-1 Chemical Structure

CAS NO. 790702-57-7

NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$260.00
100 mg
$450.00
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Biological Activity

NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability.
In vitro DMSO 69 mg/mL (174.89 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.74 mL 253.48 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18706
Actions Inhibitor
CAS No. 790702-57-7
Formula C17H22N4O3S2
M. Wt 394.51
Solubility DMSO
Purity >98%
Synonyms NGI1; NGI 1; ML414; ML 414; ML-414;
SMILES O=C(NC1=NC=C(C)S1)C2=CC(S(=O)(N(C)C)=O)=CC=C2N3CCCC3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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