NGI-1

Catalog No.: A18706
OST inhibitor
NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability.
Grouped product items
Product Name Price Stock Qty
NGI-1 5mg
Special Price $48.00 Regular Price $60.00
In stock
NGI-1 10mg
Special Price $80.00 Regular Price $100.00
In stock
NGI-1 50mg
Special Price $208.00 Regular Price $260.00
In stock
NGI-1 100mg
Special Price $360.00 Regular Price $450.00
In stock
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Biological Activity
Discription NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability.
Product Information
Catalog Num A18706
Formula C17H22N4O3S2
Molecular Weight 394.51
CAS Number 790702-57-7
SMILES O=C(NC1=NC=C(C)S1)C2=CC(S(=O)(N(C)C)=O)=CC=C2N3CCCC3
Synonyms NGI1; NGI 1; ML414; ML 414; ML-414;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 69 mg/mL (174.89 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.74 mL 253.48 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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