NH-bis(PEG3-azide) is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, NH-bis(PEG3-azide) can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized partners, making it a versatile tool in chemical biology and drug discovery research applications.
NH-bis(PEG3-azide) is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, NH-bis(PEG3-azide) can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized partners, making it a versatile tool in chemical biology and drug discovery research applications.
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