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NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.13 mL | 80.65 mL | 161.3 mL |
| 0.5 mM | 3.23 mL | 16.13 mL | 32.26 mL |
| 1 mM | 1.61 mL | 8.06 mL | 16.13 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.23 mL |
*The above data is based on the productmolecular weight 619.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15187 |
|---|---|
| Actions | Antagonist |
| CAS No. | 177707-12-9 |
| Formula | C31H24ClF6N3O2 |
| M. Wt | 619.98 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | NK 608, NK-608 |
| SMILES | C1CN(C(CC1NC(=O)C2=CC=NC3=CC=CC=C23)CC4=CC=C(C=C4)Cl)C(=O)C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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