NKP608

Catalog No.: A15187

NK1 receptor antagonist

NKP608

NKP608 Chemical Structure

CAS NO. 177707-12-9

NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

Availability: In stock

Package Price Qty
5 mg
$200.00
10 mg
$300.00
50 mg
$800.00
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Biological Activity

NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.13 mL 80.65 mL 161.3 mL
0.5 mM 3.23 mL 16.13 mL 32.26 mL
1 mM 1.61 mL 8.06 mL 16.13 mL
5 mM 0.32 mL 1.61 mL 3.23 mL

*The above data is based on the productmolecular weight 619.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15187
Actions Antagonist
M. Wt 619.98
Formula C31H24ClF6N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 177707-12-9
Synonyms NK 608, NK-608
SMILES C1CN(C(CC1NC(=O)C2=CC=NC3=CC=CC=C23)CC4=CC=C(C=C4)Cl)C(=O)C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F

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