NMS-859

Catalog No.: A21965

VCP (p97) inhibitor

NMS-859

NMS-859 Chemical Structure

CAS NO. 1449236-96-7

NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.59 mL 142.94 mL 285.89 mL
0.5 mM 5.72 mL 28.59 mL 57.18 mL
1 mM 2.86 mL 14.29 mL 28.59 mL
5 mM 0.57 mL 2.86 mL 5.72 mL

*The above data is based on the productmolecular weight 349.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21965
Actions Inhibitor
M. Wt 349.79
Formula C15H12ClN3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1449236-96-7
Synonyms NMS 859, NMS859
SMILES O=S1(C2=CC=CC=C2C(NC3=CC(NC(CCl)=O)=CC=C3)=N1)=O

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