NMS-873

Catalog No.: A12377

p97 inhibitor

NMS-873 Chemical Structure

CAS NO. 1418013-75-8

NMS-873 is a potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97 (IC50 ~0.03 uM), identified by a high-throughput screening.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $120.00

Special Price $96.00

25 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $450.00

Special Price $360.00

10mM * 1mL in DMSO
$75.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NMS-873 is a potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97 (IC50 ~0.03 uM), identified by a high-throughput screening.
Targets
p97
30 nM
In vitro DMSO 100 mg/mL (192.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.21 mL 96.03 mL 192.06 mL
0.5 mM 3.84 mL 19.21 mL 38.41 mL
1 mM 1.92 mL 9.6 mL 19.21 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12377
Actions Inhibitor
M. Wt 520.67
Formula C27H28N4O3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1418013-75-8
Synonyms NMS873, NMS 873
SMILES CC1=C(C=CC(=C1)OCC2=NN=C(N2C3=CN=CC=C3)SC4CCCC4)C5=CC=C(C=C5)S(=O)(=O)C

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy NMS-873 | NMS-873 Supplier | purchase NMS-873 | NMS-873 cost | NMS-873 manufacturer | order NMS-873 | NMS-873 distributor | buy 1418013-75-8| 1418013-75-8 Supplier | purchase 1418013-75-8 | 1418013-75-8 cost | 1418013-75-8 manufacturer | order 1418013-75-8 | 1418013-75-8 distributor
Rewards