NNC 26-9100

Catalog No.: A63865
sst4 Agonist
NNC 26-9100 is a selective full agonist of the somatostatin sst4 receptor, exhibiting a Ki of 6 nM and an EC50 of 2 nM. This compound has been demonstrated to reduce total soluble Aβ42 levels while increasing neprilysin activity in the brain, suggesting a potential role in neuroprotection. NNC 26-9100 may be valuable for research applications focused on neurodegenerative disorders and cognitive enhancement.
Grouped product items
Size Price Stock Qty
5mg
$400.00
In stock
10mg
$655.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNNC 26-9100 is a selective full agonist of the somatostatin sst4 receptor, exhibiting a Ki of 6 nM and an EC50 of 2 nM. This compound has been demonstrated to reduce total soluble Aβ42 levels while increasing neprilysin activity in the brain, suggesting a potential role in neuroprotection. NNC 26-9100 may be valuable for research applications focused on neurodegenerative disorders and cognitive enhancement.
Product Information
Catalog NumA63865
FormulaC22H25BrCl2N6S
Molecular Weight556.35
CAS Number199522-35-5
SMILESS=C(NCCCC1=CN=CN1)NCCCN(C2=NC=C(Br)C=C2)CC3=CC=C(Cl)C(Cl)=C3
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