NNC 55-0396

Catalog No.: A15188

Calcium channel blocker

NNC 55-0396

NNC 55-0396 Chemical Structure

CAS NO. 357400-13-6

NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.

Availability: In stock

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10 mg

Regular Price: $175.00

Special Price $140.00

50 mg

Regular Price: $495.00

Special Price $396.00

100 mg

Regular Price: $885.00

Special Price $708.00

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Biological Activity

NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.71 mL 88.56 mL 177.13 mL
0.5 mM 3.54 mL 17.71 mL 35.43 mL
1 mM 1.77 mL 8.86 mL 17.71 mL
5 mM 0.35 mL 1.77 mL 3.54 mL

*The above data is based on the productmolecular weight 564.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15188
Actions Blocker
CAS No. 357400-13-6
Formula C30H40Cl2FN3O2
M. Wt 564.56
Purity >98%
Synonyms NNC 55-0396 dihydrochloride
SMILES CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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