NRX-103095 is an enhancer of the interaction between β-catenin and its E3 ubiquitin ligase, SCFβ-TrCP. This compound significantly increases the binding affinity of the phosphorylated β-catenin peptide (pSer33/Ser37) for β-TrCP, exhibiting an EC50 of 163 nM. NRX-103095 is valuable for research applications focused on the Wnt/β-catenin signaling pathway and its implications in various cellular processes and diseases.
NRX-103095 is an enhancer of the interaction between β-catenin and its E3 ubiquitin ligase, SCFβ-TrCP. This compound significantly increases the binding affinity of the phosphorylated β-catenin peptide (pSer33/Ser37) for β-TrCP, exhibiting an EC50 of 163 nM. NRX-103095 is valuable for research applications focused on the Wnt/β-catenin signaling pathway and its implications in various cellular processes and diseases.
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