NSC 145669 is a potent inhibitor of tubulin polymerization, demonstrating an IC50 of 1.7 μM. This compound exhibits significant cytotoxic effects on various cancer cell lines and has shown promising antileukemic activity in murine models. NSC 145669 serves as a valuable tool for research focused on cancer biology, particularly in the study of microtubule dynamics and therapeutic strategies targeting tubulin.
NSC 145669 is a potent inhibitor of tubulin polymerization, demonstrating an IC50 of 1.7 μM. This compound exhibits significant cytotoxic effects on various cancer cell lines and has shown promising antileukemic activity in murine models. NSC 145669 serves as a valuable tool for research focused on cancer biology, particularly in the study of microtubule dynamics and therapeutic strategies targeting tubulin.
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