Biological Activity
NSC 33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.8 mL | 113.99 mL | 227.97 mL |
0.5 mM | 4.56 mL | 22.8 mL | 45.59 mL |
1 mM | 2.28 mL | 11.4 mL | 22.8 mL |
5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15389 |
---|---|
Actions | Inhibitor |
M. Wt | 438.65 |
Formula | C28H42N2O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 82058-16-0 |
Synonyms | NSC33994, NSC-33994 |
SMILES | CCC(=C(CC)C1=CC(=C(C=C1)O)CN(CC)CC)C2=CC(=C(C=C2)O)CN(CC)CC |
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