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NSC 405020


MT1-MMP inhibitor

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Catalog No. A13072

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NSC 405020 10mg A13072-10

Regular Price: €52.25

Special Price: €47.03

NSC 405020 25mg A13072-25

Regular Price: €104.50

Special Price: €94.05

NSC 405020 50mg A13072-50

Regular Price: €199.50

Special Price: €179.55

NSC 405020 100mg A13072-100

Regular Price: €342.00

Special Price: €307.80

NSC 405020 10mM * 1mL in DMSO A13072-10mM-D

Regular Price: €71.25

Special Price: €64.13

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).

NSC 405020

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Publications citing Adooq Products
NSC 405020 Citations (1)
  • Kittaka M, .et al. Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts, J Bone Miner Res, 2018, Jan;33(1):167-181 PMID: 28914985

Chemical Information

Catalog Num A13072
Actions Inhibitor
M. Wt 260.16
Formula C12H15Cl2NO
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. CAS: 7497-07-6
Synonyms NSC405020, NSC-405020

Biological Activity

NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).


Solubility (25°C) * In vitro DMSO 52 mg/mL (199.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 52 mg/mL (199.87 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.44 mL 192.19 mL 384.38mL
0.5 mM 7.69 mL 38.44 mL 76.88 mL
1 mM 3.84 mL 19.22 mL 38.44 mL
5 mM 0.77 mL 3.84 mL 7.69 mL

*The above data is based on the productmolecular weight 260.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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