NSC309401 is a potent inhibitor of dihydrofolate reductase (DHFR) from E. coli, exhibiting an IC50 value of 189 nM and a KD of 14.57 nM. This compound is essential for studying folate metabolism and can be utilized in research applications related to antimicrobial drug development and cancer therapeutics. Its specificity for DHFR makes it a valuable tool for elucidating the biochemical pathways influenced by folate synthesis.
NSC309401 is a potent inhibitor of dihydrofolate reductase (DHFR) from E. coli, exhibiting an IC50 value of 189 nM and a KD of 14.57 nM. This compound is essential for studying folate metabolism and can be utilized in research applications related to antimicrobial drug development and cancer therapeutics. Its specificity for DHFR makes it a valuable tool for elucidating the biochemical pathways influenced by folate synthesis.
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