NU 9056

Catalog No.: A13378

KAT5 (Tip60) HAT inhibitor

NU 9056 Chemical Structure

CAS NO. Not Available

NU9056 is an selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.

Availability: In stock

Package Price Qty
2 mg
$65.00
5 mg
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NU9056 is an selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.03 mL 215.17 mL 430.35 mL
0.5 mM 8.61 mL 43.03 mL 86.07 mL
1 mM 4.3 mL 21.52 mL 43.03 mL
5 mM 0.86 mL 4.3 mL 8.61 mL

*The above data is based on the productmolecular weight 232.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13378
Actions Inhibitor
M. Wt 232.37
Formula C6H4N2S4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. Not Available
Synonyms NU9056, NU-9056
SMILES C1(SSC2=CC=NS2)=CC=NS1

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