NVP-BAG956

Catalog No.: A11511
PI3K/PDK-1 Inhibitor
NVP-BAG956 acts as a potent, reversible, and ATP-competitive PI 3-K/PDK1 dual kinase inhibitor, displaying much reduced potency against VEGFR1 (IC50 = 2.56 uM) and little or no activity toward a panel of 15 other kinases (IC50 >10 uM).
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Product Name Stock
NVP-BAG956 5mg
NVP-BAG956 10mg
NVP-BAG956 25mg
NVP-BAG956 50mg
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Biological Activity
Discription NVP-BAG956 acts as a potent, reversible, and ATP-competitive PI 3-K/PDK1 dual kinase inhibitor, displaying much reduced potency against VEGFR1 (IC50 = 2.56 uM) and little or no activity toward a panel of 15 other kinases (IC50 >10 uM).
Targets
Target Value
Product Information
Catalog Num A11511
Formula C28H21N5
Molecular Weight 427.5
CAS Number 853910-02-8
SMILES CC1=NC2=CN=C3C=CC(=CC3=C2N1C4=CC=C(C=C4)C(C)(C)C#N)C#CC5=CN=CC=C5
Synonyms NVP-BAG 956
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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