NVP-TNKS656

Catalog No.: A15786

TNKS2 inhibitor

NVP-TNKS656 Chemical Structure

CAS NO. 1419949-20-4

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

Availability: In stock

Package Price Qty
5 mg
$230.00
10 mg
$400.00
25 mg
$690.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
Targets
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.1 mL 202.19 mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15786
Actions Inhibitor
M. Wt 494.58
Formula C27H34N4O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1419949-20-4
Synonyms TNKS656, TNKS-656
SMILES COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5

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