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(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium)

Catalog No.: A10673
PLK Inhibitor
ON-01910 is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium)
Grouped product items
Product Name Price Stock Qty
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium) 5mg
Special Price $48.00 Regular Price $60.00
In stock
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium) 10mg
Special Price $80.00 Regular Price $100.00
In stock
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium) 50mg
Special Price $224.00 Regular Price $280.00
In stock
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium) 100mg
Special Price $384.00 Regular Price $480.00
In stock
(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium) 10mM * 1mL in DMSO
Special Price $92.80 Regular Price $116.00
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Biological Activity
Discription ON-01910 is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.
Targets
Target Value
Product Information
Catalog Num A10673
Formula C21H24NNaO8S
Molecular Weight 473.5
CAS Number 1225497-78-8
SMILES COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-].[Na+]
Synonyms Estybon, Novonex
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C) DMSO 85 mg/mL (179.52 mM)
Water 85 mg/mL (179.52 mM)
Ethanol Insoluble
In vivo water 90 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.12 mL 105.6 mL 211.19 mL
0.5 mM 4.22 mL 21.12 mL 42.24 mL
1 mM 2.11 mL 10.56 mL 21.12 mL
5 mM 0.42 mL 2.11 mL 4.22 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Cell Cycle > Chk
Cell Cycle > PLK
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