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|Storage||at -20°C 3 years Powder|
|Synonyms||ON01910, ON 01910.Na, Estybon, Novonex, Rigosertib|
|Chemical Name||N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt|
|ON-01910 is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.|
|Solubility (25°C) *||In vitro||DMSO||95 mg/mL (200.64 mM)|
|Water||95 mg/mL (200.64 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||Saline||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||21.12 mL||105.6 mL||211.19mL|
|0.5 mM||4.22 mL||21.12 mL||42.24 mL|
|1 mM||2.11 mL||10.56 mL||21.12 mL|
|5 mM||0.42 mL||2.11 mL||4.22 mL|
*The above data is based on the productmolecular weight 473.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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