ONO 1301 is a potent prostacyclin agonist that mimics the action of prostaglandin I2. It exhibits thromboxane-synthase inhibitory activity, enhancing the production of hepatocyte growth factor (HGF) from multiple cell types. Research demonstrates that ONO 1301 effectively ameliorates ischemia-induced left ventricular dysfunction in various animal models, including mouse, rat, and pig, making it a valuable tool for studies related to cardiovascular health and regenerative medicine.
ONO 1301 is a potent prostacyclin agonist that mimics the action of prostaglandin I2. It exhibits thromboxane-synthase inhibitory activity, enhancing the production of hepatocyte growth factor (HGF) from multiple cell types. Research demonstrates that ONO 1301 effectively ameliorates ischemia-induced left ventricular dysfunction in various animal models, including mouse, rat, and pig, making it a valuable tool for studies related to cardiovascular health and regenerative medicine.
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