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Ortataxel

Catalog No.: A54945
Antitumor Agent
Ortataxel is a novel antitumor agent that functions as a microtubule stabilizer, effectively disrupting cell division. It demonstrates significant cytotoxic activity against various drug-sensitive and resistant cancer cell lines, making it a valuable tool for cancer research. Its potential applications include assessing drug resistance mechanisms and exploring combination therapies in preclinical studies.
Ortataxel 186348-23-2 Antitumor Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOrtataxel is a novel antitumor agent that functions as a microtubule stabilizer, effectively disrupting cell division. It demonstrates significant cytotoxic activity against various drug-sensitive and resistant cancer cell lines, making it a valuable tool for cancer research. Its potential applications include assessing drug resistance mechanisms and exploring combination therapies in preclinical studies.
Product Information
Catalog NumA54945
FormulaC44H57NO17
Molecular Weight871.92
CAS Number186348-23-2
SMILESCC(C)C[C@H](NC(OC(C)(C)C)=O)[C@@H](O)C(O[C@@H]([C@]1([H])OC(O[C@@]12[C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]5(C)[C@@H](O)C[C@]6([H])[C@@]4(OC(C)=O)CO6)=O)C(C)=C(C2(C)C)[C@@H](OC(C)=O)C5=O)=O
SynonymsIDN 5109; BAY 59-8862
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Cytoskeleton > Microtubule/Tubulin