Catalog No.: A17048

SIRT 6 inhibitor


OSS-128167 Chemical Structure

CAS NO. 887686-02-4

OSS-128167, also known as SIRT6-IN-1, is a potent and selective SIRT 6 inhibitor with IC50 value of 89 μM.

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Biological Activity

OSS-128167, also known as SIRT6-IN-1, is a potent and selective SIRT 6 inhibitor with IC50 value of 89 μM.
In vitro (25°C) DMSO 68 mg/mL (185.62 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.3 mL 136.49 mL 272.98 mL
0.5 mM 5.46 mL 27.3 mL 54.6 mL
1 mM 2.73 mL 13.65 mL 27.3 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17048
Actions Inhibitor
CAS No. 887686-02-4
Formula C19H14N2O6
M. Wt 366.33
Purity >98%
Synonyms OSS128167, OSS 128167, SIRT6-IN-1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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