Catalog No.
Product Name
Application
Product Information
Citations
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Impurity
Captopril EP Impurity D is identified as an impurity associated with Captopril, an angiotensin-converting enzyme (ACE) inhibitor. It serves as a reference standard in pharmaceutical quality control and analytical testing to ensure the purity and compliance of Captopril formulations. This compound is critical for researchers monitoring the chemical profile and safety of ACE inhibitors in drug development and therapeutic applications. -
Chlorthalidone Impurity
Chlorthalidone impurity is a metabolite of the thiazide-like diuretic Chlorthalidone, primarily targeting sodium reabsorption in the renal tubules. This impurity is important for studies involving metabolic pathways and pharmacokinetics of Chlorthalidone. It is particularly relevant for research into hypertension treatment and the identification of potential off-target effects or interactions. -
Drug intermediate
4-Methoxybenzenecarbothioamide is a synthetic intermediate primarily employed in pharmaceutical synthesis. This compound is synthesized through the reaction of 4-methoxybenzamide with phosphorus pentasulfide, facilitating the creation of various thioamide derivatives. Its unique structure and reactivity make it a valuable building block for the development of biologically active molecules in chemical research. -
Vardenafil Impurity
Vardenafil N-oxide is an N-Oxide impurity of Vardenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor. This compound serves as an important analytical standard for quality control and characterization of Vardenafil formulations in pharmaceutical research. Its presence may impact the pharmacokinetics and efficacy of Vardenafil, making it relevant for studies on drug metabolism and safety assessments. -
Simvastatin Impurity
Anhydrosimvastatin is an impurity of Simvastatin, a known competitive inhibitor of HMG-CoA reductase, which plays a crucial role in cholesterol biosynthesis. This compound is primarily used in research to assess the purity and quality of Simvastatin preparations. Its characterization is essential for studies evaluating the pharmaceutical formulations and metabolic pathways influenced by cholesterol-lowering therapies. -
Trityl olmesartan medoxomil Impurity
Trityl olmesartan medoxomil impurity III is a characterized impurity of Trityl olmesartan medoxomil, which itself serves as an intermediate in the synthesis of Olmesartan medoxomil. This compound is utilized in chemical research to evaluate the purity of olmesartan formulations and assess related synthesis methods. Its presence as an impurity is crucial for understanding the intricacies of drug development and quality control processes within the pharmaceutical industry. -
Atorvastatin Impurity
Difluoro atorvastatin is an impurity of the HMG-CoA reductase inhibitor atorvastatin. This compound demonstrates significant activity by effectively reducing blood lipid levels. Additionally, difluoro atorvastatin is known to inhibit the proliferation and invasion of human smooth muscle cells, exhibiting IC50 values of 0.39 μM and 2.39 μM, respectively. It serves as a useful reference compound in the evaluation of atorvastatin purity and related studies in cholesterol management and cardiovascular research. -
Febuxostat Impurity
Febuxostat impurity 7 is a chemical impurity related to Febuxostat, a selective xanthine oxidase inhibitor with a Ki value of 0.6 nM. This impurity is important for quality control and characterization in drug development and analytical chemistry applications involving Febuxostat. Understanding its properties can aid in assessing the purity and stability of formulations containing Febuxostat. -
Daclatasvir Impurity
Daclatasvir Impurity C is a chemical impurity associated with Daclatasvir, a potent inhibitor of the Hepatitis C virus (HCV) NS5A protein. Its characterization is essential for assessing the purity and quality of Daclatasvir in pharmaceutical formulations. This reagent is valuable for researchers focusing on the pharmacological properties of antiviral compounds and for ensuring compliance in drug development processes. -
Hydroxychloroquine Impurity
Hydroxychloroquine Impurity F is a structural impurity associated with Hydroxychloroquine, a synthetic antimalarial agent. This compound demonstrates the ability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling pathways. Hydroxychloroquine has also been shown to effectively inhibit SARS-CoV-2 infection in vitro, making it a significant focus of research in virology and immunology. -
Prasugrel Impurity
Prasugrel chloride impurity is a chemical impurity associated with Prasugrel, extracted from patent US20130345428A1, line 0053. Prasugrel serves as a potent and orally active antagonist of the P2Y12 receptor, effectively inhibiting ADP-induced platelet aggregation. This reagent is useful for research applications related to platelet function and thrombotic disorders, aiding in the assessment of drug purity and compliance in pharmaceutical formulations. -
Impurity of Cetirizine 3-chloro
Cetirizine 3-chloro impurity is a structural variant of Cetirizine 3-chloro, primarily analyzed for its potential effects on pharmacological activity. As an impurity, it is relevant in various quality control and analytical chemistry applications when assessing the purity of Cetirizine formulations. The characterization of this impurity is essential for ensuring the safety and efficacy of related pharmaceutical products. -
Atorvastatin Impurity
3-Oxo Atorvastatin is an impurity of atorvastatin, which acts as an HMG-CoA reductase inhibitor. This compound is critical in studying the metabolic pathways associated with cholesterol synthesis and lipid regulation. Its role as an impurity is essential for accurately assessing the purity and efficacy of atorvastatin in pharmaceutical formulations and research applications. -
Remdesivir Impurity
Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of the antiviral agent Remdesivir, a nucleoside analogue primarily targeting viral RNA synthesis. This compound is relevant in assessing the purity and efficacy of Remdesivir, which has demonstrated potent antiviral activity against SARS-CoV and MERS-CoV, with EC50 values of 74 nM in human airway epithelial cells and 30 nM against murine hepatitis virus in delayed brain tumor cells. Research involving this impurity can aid in the development and validation of antiviral therapeutics, particularly in the context of COVID-19. -
Gefitinib Impurity
Gefitinib impurity 1 is a known impurity associated with the tyrosine kinase inhibitor gefitinib, which specifically targets the epidermal growth factor receptor (EGFR). This compound plays a role in research applications aimed at understanding gefitinib's mechanism of action and its effects on EGF-stimulated tumor cell proliferation. Gefitinib demonstrates a potent inhibitory effect on EGFR autophosphorylation and tumor cell growth, making it valuable for studies related to cancer therapeutics and the exploration of resistance mechanisms in oncological research. -
Macamide Impurity
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide is a known impurity of Macamide, primarily utilized in the study of lipid metabolism and signaling pathways. This compound can be valuable for researchers investigating the biological effects of macamide derivatives and their potential role in modulating cellular processes. Its distinct chemical structure allows for the exploration of its impacts on various biological systems. -
Drug Impurity
Clozapine impurity 3 is a known impurity associated with the antipsychotic agent Clozapine. It serves as a critical reference material for assessing the purity and quality of Clozapine formulations. This reagent is essential for research and analytical applications focused on drug development, impurity profiling, and safety assessments of pharmaceutical compounds. -
Cetilistat Impurity
Cetilistat impurity 1 is a known impurity of the anti-obesity agent Cetilistat, which inhibits pancreatic lipase. This compound demonstrates significant biological activity, inhibiting both rat and human pancreatic lipase with IC50 values of 54.8 nM and 5.95 nM, respectively. It is primarily utilized in research to assess the purity and efficacy of Cetilistat and related formulations in obesity-related studies. -
Daclatasvir Impurity
Daclatasvir Impurity B is an impurity of the antiviral agent Daclatasvir, which targets the HCV NS5A protein. This compound is significant for quality control and analytical purposes in the synthesis and formulation of Daclatasvir. It may also be utilized in research applications aimed at understanding the pharmacological properties and stability of Daclatasvir. -
MOF
Butane-1,4-diyldiphosphonic acid is a versatile linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). Targeting metal-organic frameworks (MOFs), this compound facilitates the conjugation of target proteins to E3 ligases, allowing for enhanced targeted degradation. Its unique alkyl chain structure supports various applications in drug development and protein degradation studies, contributing to advancements in therapeutic strategies. -
Drug Intermediate
Allyl-mannose-6-phosphonate is a stable analogue of mannose-6-phosphate, serving as a valuable drug intermediate. This compound facilitates the synthesis of M6P-peptide conjugates and the development of lysosome-targeting chimeras (LYTAC), making it essential in various bioconjugation research applications. Its unique properties enable advancements in targeted drug delivery systems and lysosomal targeting strategies in biomedical research. -
Ester Product
6-Azidohexanoic acid is an azide-containing fatty acid derivative that serves as a versatile building block for the synthesis of esters. This compound is particularly valuable in chemical biology, enabling the introduction of azide functionalities into various biomolecules for applications such as click chemistry and bioconjugation. Its unique reactive properties facilitate the study of protein labeling, cellular imaging, and the development of biolabels. -
Biochemical Assay Reagent
8-Aminooctanoic acid is an omega-amino fatty acid with an amino group at the C8 position of octanoic acid. As a human metabolite, it acts as a biochemical assay reagent, providing insights into metabolic pathways and cellular functions. Its applications include studying metabolic disorders and evaluating fatty acid metabolism in various biological systems. -
Biochemical Assay Reagents
Resorufin β-D-glucuronide sodium serves as a substrate for the enzyme β-glucuronidase, facilitating the assessment of enzyme activity in various biochemical assays. This compound is particularly valuable for studies involving drug metabolism, pharmacokinetics, and the investigation of glucuronidation processes. Its utility in fluorescence-based assays allows for sensitive detection and quantification of β-glucuronidase activity in biological samples. -
Ziprasidone Impurity
6-Chloro-5-(2-chloroethyl)oxindole is a known impurity of Ziprasidone, which primarily targets the human dopamine transporter (hDAT). This compound serves as an important reference standard for assessing the purity of Ziprasidone in pharmaceutical research. It is utilized in studies related to dopaminergic activity and may aid in the development of antipsychotic medications. -
Biochemical Reagent
Pomalidomide-PEG2-OH is an E3 ligase ligand-linker conjugate featuring a pomalidomide-derived cereblon ligand connected via a two-unit polyethylene glycol (PEG) linker. This compound facilitates targeted protein degradation by promoting the recruitment of specific substrates to the cereblon E3 ligase complex. It serves as a useful biochemical reagent in drug discovery and development, particularly for the study of protein homeostasis and therapeutic applications in oncology. -
Biochemical Reagent
Pomalidomide-PEG3-OH is a biochemical reagent that functions as an E3 ligase ligand-linker conjugate. It consists of a pomalidomide-derived ligand for cereblon fused with a three-unit polyethylene glycol (PEG) linker. This compound is designed for studies involving targeted protein degradation and facilitates the investigation of protein interactions within cellular processes. Its unique structure enables researchers to explore novel therapeutic strategies in cancer and other diseases reliant on E3 ligase activity. -
Biochemical Reagent
Thalidomide-5-Br is a biochemical reagent targeting bromodomains. This compound exhibits significant anti-inflammatory and potential anti-tumor activities, making it a valuable tool in the study of inflammation and tumor biology. It is also relevant for neurological research applications, contributing to a deeper understanding of various disease mechanisms. -
Impurity of Sirolimus
Sirolimus isomer C is an impurity of Sirolimus, a macrolide compound that acts through the inhibition of the mammalian target of rapamycin (mTOR). This compound is primarily used for quality control assessments and method development in pharmaceuticals. Its characterization is crucial for ensuring the purity and efficacy of Sirolimus formulations in research and clinical applications. -
Ester Product
1,16-Hexadecanediol serves as a diol compound recognized for its role in esterification reactions. It exhibits significant utility in pharmaceutical synthesis and the development of polymeric materials. This compound can be employed in various research applications, including the preparation of surfactants and lubricants, contributing to advancements in material science and biophysical studies. -
Ester Product
DHA Ceramide is a ceramide derivative featuring docosahexaenoic acid (C22:6) as its fatty acyl component. This ester product plays a crucial role in cellular functions, including membrane structure and signaling processes. It is commonly utilized in research focused on skin hydration, barrier function, and the regulation of inflammatory responses, making it valuable in studies related to dermatology and lipid biochemistry. -
Biochemical Indice
Sodium Sulphanilate is a biochemical indicator utilized in the study of inflammation-associated acute-phase responses. It serves as a valuable tool for researchers investigating the dynamics of inflammation and the associated physiological changes. Its use in various experimental models aids in understanding the underlying mechanisms of inflammatory diseases and the effectiveness of therapeutic interventions. -
Ester Product
9-Oxooctadecanoic acid, also known as 9-Oxostearic acid or 9-Ketostearic acid, is an ester derivative with important relevance in biochemical research. This compound exhibits distinctive biological activities, including modulation of lipid metabolism and potential implications in fatty acid oxidation pathways. It serves as a valuable tool for studying metabolic processes and understanding the role of lipids in cellular functions. -
Ester Product
C16-Dihydroceramide, also known as N-Palmitoyl sphinganine, is an ester derivative involved in sphingolipid metabolism. It plays a critical role in cellular signaling pathways, particularly in the regulation of cell growth and apoptosis. C16-Dihydroceramide is utilized in research focused on cancer biology, lipid metabolism, and the study of cell membrane dynamics. Its biological activity makes it a valuable tool for investigations into skin biology and neurodegenerative disorders. -
Ester Product
(R)-3-Hydroxytetradecanoic acid is an ester compound that serves as a fatty acid derivative. It exhibits significant biological activity and can be utilized in the study of lipid metabolism and signaling pathways. This reagent is valuable for researchers investigating the roles of fatty acids in cellular processes and their implications in various biological systems. -
Ester Product
Oxiran-2-ylmethanol, also known as Glycidol, is an ester compound known for its ability to induce base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. This compound forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts, indicating its potential as a carcinogen in animal models without significantly inducing micronucleated immature erythrocytes in bone marrow. Additionally, Oxiran-2-ylmethanol serves as a key reagent for anionic polymerization, facilitating the synthesis of linear poly(glycidol), and is applicable in cancer research. -
Ester Product
Propyl dodecanoate is an ester compound primarily used in organic synthesis. This reagent serves as a solvent and esterification agent in various chemical reactions, facilitating the formation of long-chain fatty acids and their derivatives. Its applications extend to the study of lipid metabolism and the development of fragrance and flavor compounds in the food and cosmetic industries. -
Biochemical Assay Reagent
C26-Ceramide is a long-chain sphingolipid that serves as an important biochemical assay reagent. It possesses 26 carbon atoms in its hydrophobic tails, one saturated and one unsaturated, rendering it suitable for various applications in lipid research. C26-Ceramide can be utilized in the formulation of lipid nanoparticles or liposomes, contributing to studies in membrane biology, drug delivery, and cellular signaling pathways. -
Ester Product
18-HEPE (18-Hydroxy-5(Z),8(Z),11(Z),14(Z),16(E)-eicosapentaenoic acid) is an ester derivative that plays a crucial role in modulating inflammatory responses. This compound exhibits significant biological activity as a lipid mediator, influencing various cellular signaling pathways. Research applications include studies on inflammation, lipid metabolism, and the development of therapeutic agents targeting related diseases. -
Nonsteroidal Anti-inflammatory Drug
Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID) primarily targeting the inhibition of cyclooxygenase enzymes. This compound exhibits significant anti-inflammatory and analgesic properties, making it valuable in the study of rheumatoid arthritis and related inflammatory disorders. Researchers can utilize Azapropazone to investigate its effects on pain management and the underlying mechanisms of inflammatory conditions. -
Metal-organic Framework
UIO-66-(OH)2 is a metal-organic framework (MOF) that exhibits strong thermal stability and high surface area. This compound serves as an effective adsorbent and has applications in gas storage, separation, and catalysis. Its hydroxyl functional groups enhance its potential for diverse chemical interactions, making it suitable for various research applications in materials science and environmental remediation. -
Ester Product
Para-nitrophenyl oleate is an ester compound known for its role as a substrate in enzymatic assays. It acts as a colorimetric indicator for lipases, facilitating the measurement of their activity in biochemical research. This reagent is widely utilized in studies involving lipid metabolism and enzyme kinetics. -
Ester Product
(Z)-Hexadec-9-enamide, also known as palmitoleamide, is an ester derivative with biochemical significance. It exhibits a range of biological activities, including anti-inflammatory and neuroprotective effects. This compound is widely utilized in research applications aimed at exploring lipid signaling pathways and developing therapeutic approaches for neurological disorders. -
Ester Product
C24 Dihydro ceramide (d18:0/24:0) is an ester product with a primary mechanism of targeting ceramide metabolism. This compound plays a crucial role in the sphingolipid pathway and is instrumental in studies of cell signaling, apoptosis, and cellular stress responses. Its unique structure and biological activity make it a valuable reagent for researchers investigating lipid-related pathways and their implications in various diseases. -
Ester Product
C18 Dihydroceramide is a sphingolipid derivative characterized by its ester structure. This compound plays a crucial role in cellular processes, including membrane formation and signaling pathways. It is primarily utilized in research applications investigating lipid metabolism, cell signaling, and the impact of sphingolipids on various biological functions. -
Ester Product
6-Methylheptanoic acid is a medium-chain fatty acid derivative that acts as an ester product. It is utilized in various chemical syntheses and serves as an important intermediate in lipid metabolism studies. This compound can be applied in the development of flavoring agents, fragrances, and surfactants, contributing to research in biochemistry and organic chemistry. -
Ester Product
Pentadecanedioic acid, also known as 1,13-tridecanedicarboxylic acid, serves as a dicarboxylic acid with versatile applications in organic synthesis. Its ester derivatives are utilized in the production of surfactants, lubricants, and plasticizers, demonstrating distinctive properties that enhance material performance. This compound is valuable in various chemical research applications, including the development of biodegradable polymers and other specialty chemicals. -
Ester Product
18-Hydroxyoctadecanoic acid is an ester derivative of octadecanoic acid, primarily recognized for its role in lipid metabolism. This compound exhibits significant biological activity, influencing various metabolic pathways and cellular processes. It serves as a valuable research tool in studies related to fatty acid signaling, lipid biochemistry, and the regulation of energy homeostasis. -
Ester Product
C24:1-Dihydro-ceramide is an ester product characterized by its role as a pivotal lipid mediator. This compound is involved in various cellular processes, including apoptosis and cell signaling pathways. It serves as a valuable tool in studies investigating sphingolipid metabolism, cell differentiation, and pathological conditions related to dysregulated lipid signaling. Its unique properties make it suitable for research in cancer biology and neurodegeneration. -
Sedative-Hypnotic Neuroactive Steroid
Posovolone is a sedative-hypnotic neuroactive steroid that exerts its effects through modulatory actions on the GABA-A receptor. Demonstrating notable anticonvulsant and anxiolytic-like activities, posovolone may also elicit ataxic effects. This compound is applicable in research exploring neuropharmacology, anxiety disorders, and seizure management.
