Oxomemazine

Catalog No.: A33903
Histamine H1-Receptor Blocker
Oxomemazine is a phenothiazine-derived antagonist targeting the histamine H1 receptor. It exhibits notable antihistamine and anticholinergic properties, making it useful in research related to cough treatments. Additionally, Oxomemazine demonstrates a selective blockade of the muscarinic M1 receptor with a significant affinity difference compared to the M2 receptor. Studies have shown its protective effects against anaphylactic microshock in guinea pigs, highlighting its potential for further pharmacological investigation.
Grouped product items
Size Price Stock Qty
5mg
$20.00
In stock
10mg
$25.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOxomemazine is a phenothiazine-derived antagonist targeting the histamine H1 receptor. It exhibits notable antihistamine and anticholinergic properties, making it useful in research related to cough treatments. Additionally, Oxomemazine demonstrates a selective blockade of the muscarinic M1 receptor with a significant affinity difference compared to the M2 receptor. Studies have shown its protective effects against anaphylactic microshock in guinea pigs, highlighting its potential for further pharmacological investigation.
Product Information
Catalog NumA33903
FormulaC18H22N2O2S
Molecular Weight330.44
CAS Number3689-50-7
SMILESCC(CN1C2=C(C=CC=C2)S(C3=CC=CC=C13)(=O)=O)CN(C)C
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