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Biological Activity
P110δ-IN-1 is a potent and selective inhibitor of P110δ extracted from patent WO 2014055647 A1, with an IC50 of 8.4 nM.
| In vitro | DMSO | 18 mg/mL (29.76 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.54 mL | 82.68 mL | 165.35 mL |
| 0.5 mM | 3.31 mL | 16.54 mL | 33.07 mL |
| 1 mM | 1.65 mL | 8.27 mL | 16.54 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.31 mL |
*The above data is based on the productmolecular weight 604.774. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18348 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1595129-71-7 |
| Formula | C31H40N8O3S |
| M. Wt | 604.774 |
| Purity | >98% |
| Synonyms | ME401, ME 401, PWT143, PWT 143, PWT-143 |
| SMILES | O=S(C1=NC2=CC=CC=C2N1C3=NC(N4CCOCC4)=NC(NC(C)(C)CC5=CC=CC=C5C6CCN(C)CC6)=N3)(C)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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